Quercetin: Bridging Traditional Chinese Medicine and Modern Neuroscience in Amnesia Treatment

Abstract

Treatment of amnesia, a debilitating cognitive disorder associated with age and neurodegenerative disorders, remains a formidable obstacle. Traditional Chinese medicine (TCM) makes use of quercetin, a dietary flavonoid known for its neuroprotective benefits, as discussed in thisreview. Notably, quercetin is linked to several TCM remedies, including Jiang Huang (Curcuma longa) and He Shou Wu (Fo-ti), which have longbeen used for their restorative effects on cognitive function and the prevention of memory loss. According to TCM, these formulas promotebetter mental health by strengthening the circulatory and endocrine systems and boosting blood flow. This review explores the molecular basisof quercetin’s neuroprotective advantages, focusing on its role in oxidative stress control, neuroinflammation reduction, and synaptic plasticityaugmentation. We investigated novel methods of quercetin delivery to increase its therapeutic efficacy, solve pharmacokinetic limitations, andcritically assess clinical and preclinical data. In addition, we explored possible future research directions and translational implications forneurodegenerative illnesses, drawing attention to quercetin’s abilities as an anti-inflammatory, effective antioxidant, and an important partof TCM. TCM emphasizes quercetin’s ability to improve the quality of life and restore cognitive function by employing it in comprehensivetherapy regimens.