Journal of Advanced Scientific Research https://www.sciensage.info/index.php/JASR <p><strong>Journal of Advanced Scientific Research (ISSN: 0976-9595) is a peer-reviewed online journal, published&nbsp;Monthly. This Journal publishes original research work, reviews, and short communications that contributes significantly to further the scientific knowledge in the subject areas of Chemistry, Pharmaceutical Research, Biochemistry, Microbiology, Biotechnology,&nbsp; Medicine and applied Biosciences to all the destinations for faster connectivity to respective research, taking due care of speed and pace of knowledge generation.</strong></p> Sciensage en-US Journal of Advanced Scientific Research 0976-9595 TiO2-SiO2 Nanoparticles with UV-shielding Effect and Reduced Photocatalytic Activity https://www.sciensage.info/index.php/JASR/article/view/2485 <p>Here, we present the synthesis of multifunctional nanoparticles with suppressed photocatalytic activity, tremendous photoluminescence, great optical transparency and outstanding UV absorbance. The nanoparticles’ shape is shown by FESEM tests as fibrous linkages that resemble rods and have pores in between. According to the BJH analysis, the measured pore size was 20 nm. Ultraviolet light irradiation tests confirm the highly effective UV screening performance; nevertheless, the nanoparticles’ photocatalytic property was removed. In the whole 200 to 400 nm range, the UV transmittance is comparatively low, demonstrating the sample’s improved UV protection capability. The nanoparticles’ ultralow dimension, 2.49 m2 g-1 was discovered during a nitrogen adsorption/desorption test, which is in line with their phenomenally low photocatalytic capacity.</p> Bharati Debi Biswas ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc-sa/4.0 2025-09-30 2025-09-30 16 09 1 7 10.55218/JASR.2025160901 Synthesis, Characterisation and Biological Assessment of 2,4,6-Trisubstituted 1,3,5-Triazine Derivatives https://www.sciensage.info/index.php/JASR/article/view/2488 <p>2,4,6-trichloro-1,3,5-triazine (Cyanuric Chloride) and 4-(4-aminophenyl)morpholin-3-one were converted into a new series of 2,4,6-trisubstituted 1,3,5-triazine derivatives by a regioselective reaction, which was followed by reflux with substituted thiophenole in the presence of a catalytic amount of triethyl amine. IR, 1H-NMR, mass, and elemental analysis were used to characterise each of the synthesised substances. All the synthesized compounds were tested for their in vitro antimicrobial activity against gram-positive strains, such as Staphylococcus aureus and Bacillus subtilis, as well as gram-negative strains, such as Escherichia coli and Pseudomonas aeruginosa, by using ampicillin, chloramphenicol and tetracycline as standard drugs. In-vitro antifungal activity was tested against three different fungal strains, such as Candida albicans, Aspergillus flavus and Aspergillus niger. Most of the compounds showed moderate to good activity. Among them, compound CML-1F is most active against bacterial species and compound CML-1H exhibited potent antifungal activity.</p> Mayur L. Chandera Kinjal J. Sabalpara Chetana M. Rajyaguru Jatin J. Upadhyay ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc-sa/4.0 2025-09-30 2025-09-30 16 09 8 14 10.55218/JASR.2025160902